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对36例急性心肌梗塞患者采用国产尿激酶进行冠状动脉腔内溶栓治疗。冠状动脉再通27例(75％)、未通9例(25％)。再通率有随年龄增大和梗塞发生至溶栓开始时间的增加而下降;尿激酶用量则与年龄和梗塞发生至溶栓开始时间的增加而增加的倾向。27例再通者中,出现再灌注性心律紊乱者24例(88.9％),ST段显著下移25例(92.5％),心绞痛明显缓解者26例(96.3％)。证明国产尿激酶具有良好的溶栓作用。
Thirty-six patients with acute myocardial infarction were treated with domestic urokinase for intra-arterial thrombolysis. Coronary artery recanalization in 27 cases (75%), failed in 9 cases (25%). The recanalization rate decreased with age and the onset of infarction until initiation of thrombolysis; the amount of urokinase tended to increase with age and onset of infarction until onset of thrombolysis. Of the 27 recanalisors, 24 (88.9%) had reperfusion arrhythmia, 25 (92.5%) had a significant decrease in ST, and 26 (96.3%) had remission of angina pectoris. Prove that domestic urokinase has a good thrombolytic effect.