抗真菌新药环吡酮胺具有结构新、抗菌谱广、毒性小等特点。它与目前常用的咪唑类抗真菌药的结构完全不同,优于国内其它同类药物,是国家医药总局确定的八五期间重点开发研究的国家级新药。它不仅抗真菌活性显著,还对各种革兰氏阳性及革兰氏阴性细菌及支原体、衣原体、毛滴虫等也都有抑制作用,尤其对使皮肤角化的真菌有高效,该药具有较高的治疗指数。该药的研制成功为我国增添了抗真菌药新品种。为广大军民皮肤病及甲癣病患者解除病痛。我们经过不断的摸索、考察与完善,建立了一套实用于工业化生产的工艺路线,成功 Antifungal drug Ciclopirox olamine has a new structure, broad antibacterial spectrum, toxicity and other characteristics. It is completely different from the current commonly used imidazole antifungal agents and is superior to other similar drugs in the country. It is a state-level new drug that has been mainly researched and developed by the State Administration of Medicine during the period of the Eighth Five-Year Plan. It is not only antifungal activity is significant, but also for a variety of Gram-positive and Gram-negative bacteria and mycoplasma, chlamydia, trichomoniasis, etc. also have an inhibitory effect, especially for skin keratosis fungi have high efficiency, the drug has Higher therapeutic index. The success of the drug development for our country added a new antifungal drug varieties. For the majority of military and civilian skin and onychomycosis patients relieve illness. After continuous exploration, investigation and improvement, we have established a set of practical industrial process routes, the success