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目的分析新生儿应激性溃疡的治疗特点,探讨采用奥美拉唑胃管注入法治疗新生儿应激性溃疡的治疗效果。方法选择我院自2008年2月至2010年4月所收治的新生儿应激性溃疡患者共152例,将其随机分成两组,观察组与对照组,各76例。对照组采取常规性治疗法,而观察组在常规治疗法的基础上辅以奥美拉唑胃管注入治疗,具体为采取胃管注入奥美拉唑,剂量为0.6mg/kg,1次/d,连续使用5d。维持治疗持续到胃回抽物不再有咖啡样液体后,再行治疗1d。结果两组的治疗总有效率分别为,观察组96.8%,对照组73.6%,两组比较差异有统计学意义(P<0.05)。结论奥美拉唑胃管注入治疗对新生儿应激性溃疡的效果较明显,与常规治疗法相比,更有利于患儿的康复,值得临床应用推广。
Objective To analyze the therapeutic characteristics of neonatal stress ulcer and to explore the therapeutic effect of omeprazole in gastric ulcer. Methods 152 cases of neonatal stress ulcer admitted to our hospital from February 2008 to April 2010 were randomly divided into two groups, observation group and control group, each with 76 cases. The control group to take conventional therapy, while the observation group on the basis of conventional therapy with omeprazole gastric tube injection, specifically to take omeprazole into the stomach, a dose of 0.6mg / kg, 1 / d, continuous use 5d. Maintenance treatment continued until the gastric juice is no longer a coffee-like liquid, and then treatment 1d. Results The total effective rates of the two groups were 96.8% in the observation group and 73.6% in the control group, respectively, with significant difference between the two groups (P <0.05). Conclusion Omeprazole gastric tube injection therapy is more effective in neonatal stress ulcer. Compared with conventional treatment, it is more conducive to the rehabilitation of children, which is worth popularizing in clinical application.