从1995年～1998年深圳市站门诊饮食、服务行业从业人员健康体检人员332 445例肛拭子大便培养中共分离出志贺氏菌1242株,阳性率为0.37％,其中以B群居首,为999株,占志贺氏菌属80.06％,B群中又以2a亚型为首占82.88％,其次为D群,为199株,占16.02％,不同年度均以B群比例增高,但年度差异较大(P<0.005),D群分布年度间差异也十分明显(P<0.005) From 1995 to 1998, there were 1242 Shigella isolates isolated from 332 445 rectal swabs from health check-ups of food and service practitioners in the outpatient service of Shenzhen Station. The positive rate was 0.37% Accounting for 80.06% of all isolates. In group B, 82.88% of them belonged to 2a subtype, followed by D group and 199 strains, accounting for 16.02%, all of which were increased in group B in different years. However, (P <0.005), and the distribution of D group was also significantly different between years (P <0.005)