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本文报道了得自 Pseudoaxinyssa sp(来自澳大利亚礁石的一种海绵)中三个具有高分支侧链的新甾醇(25—甲基岩藻甾醇、24—甲基—24—乙基胆甾醇和 axinyssasterol)的分离,结构测定和化学合成并且提出了该海绵中所有甾醇的生物合成关系。Hofheinz 和 Oesterhelt 曾报导该海绵只含有24—异丙基胆甾醇(1)和其22—脱氢同系物(2)及24—异丙叉基胆甾醇(3),成为唯一的具有24—异丙基取代的天然海洋甾
Three new sterols (25-methylfucosterol, 24-methyl-24-ethylcholesterol and axinyssasterol) with high branching side chains from Pseudoaxinyssa sp (a sponge from Australian reefs) Separation, structure determination and chemical synthesis and proposed the biosynthesis of all sterols in this sponge. Hofheinz and Oesterhelt have reported that the sponge contains only 24-isopropylcholesterol (1) and its 22-dehydrogenated homologues (2) and 24-isopropylidenecholesterol (3) Propyl-substituted natural marine steroid