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40年来原发性高血压(EH)的治疗取得很大成就,延长和挽救了无数病人的生命。直至最近治疗EH的主要目标是不惜任何代价降低血压,一种药物无效另加其它降压药,多种降压药递增和增加剂量直至血压下降至满意水平。长期以来流行的阶梯治疗能明显降低脑卒中和心力衰竭的发病率但不能明显降低冠心病的发病率。
40 years of treatment of essential hypertension (EH) made great achievements, extending and saving the lives of countless patients. Until recently, the primary goal of treating EH was to lower blood pressure at any cost, with one drug ineffective plus other antihypertensive drugs, multiple antihypertensive drugs increasing and increasing doses until blood pressure dropped to a satisfactory level. The long-standing epidemic of stepladder therapy has been shown to significantly reduce the incidence of stroke and heart failure but not significantly reduce the incidence of coronary heart disease.