放置宫内节育器（ＩＵＤ）后预防性给予宫宁颗粒剂５０例（预防组），与置器后不服药者５０例（对照组）进行了比较。结果表明，预防组月经血量、经期天数、周期天数、血红蛋白与置器前比较均无明显差异（Ｐ＞０．０５），月经血量、经期天数低于对照组，周期天数、血红蛋白高于对照组，均有非常显著性差异（Ｐ＜０．００１）。置器后月经异常的发生率分别为８％、６６％，预防性给予本药可显著降低放置ＩＵＤ后月经异常的发生率 Fifty patients (prevention group) were given preventive prophylaxis with Gongning granule after intrauterine device placement (IUD), and 50 patients (control group) were treated with intrauterine device (IUD). The results showed that there was no significant difference in the amount of menstrual blood, the days of menstruation, the number of days, the hemoglobin in precautionary group compared with the pre-instrumentation (P> 0.05), the menstrual blood volume, the days of menstruation were lower than the control group, the number of cycles, hemoglobin Control group, there was a very significant difference (P <0.001). The incidence of menstrual abnormalities after device placement were 8% and 66%, respectively. Preventive administration of this drug significantly reduced the incidence of menstrual abnormalities after IUD placement