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目的观察瑞芬太尼用于小儿扁桃体和腺样体切除术麻醉维持的有效性及安全性。并与氯胺酮比较术中MAP、HR变化。术后生理反射功能恢复及不良反应。方法 60例患儿随机分为丙泊酚瑞芬太尼组(P-R组),氯胺酮丙泊酚组(K-P组),每组30例,记录在扁桃体切除,术毕,拔管,出室时MAP、HR值,术毕生理反射功能恢复时间及术后不良反应的发生。结果术中P-R组MAP、HR略低(P<0.05),但在正常范围。术后自主呼吸恢复两组无明显差异,其它生理反射功能恢复P-R组时间显著缩短(P<0.01)。但P-R组躁动率较高。结论丙泊酚瑞芬太尼用于小儿扁桃体和腺样体切除术中麻醉维持。术中平稳,术后苏醒迅速,并发症少,安全、有效。
Objective To observe the effectiveness and safety of remifentanil in the anesthesia maintenance of pediatric tonsil and adenoidctomy. And compared with ketamine intraoperative MAP, HR changes. Postoperative physiologic reflex function recovery and adverse reaction. Methods Sixty children were randomly divided into three groups: propofol remifentanil group (PR group) and ketamine propofol group (KP group), 30 cases in each group, which were recorded in tonsillectomy, operation complete, extubation, MAP, HR value, recovery time of physiologic reflex function and postoperative adverse reaction. Results The intraoperative P-R group MAP and HR were slightly lower (P <0.05), but in the normal range. Postoperative spontaneous breathing recovery was no significant difference between the two groups, other physiological reflex function recovery P-R group was significantly shorter (P <0.01). However, P-R group higher agitation rate. Conclusion Propofol remifentanil is used to maintain anesthesia in children with tonsil and adenoidctomy. Intraoperative stable, rapid recovery after surgery, fewer complications, safe and effective.