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目的探讨基底节内囊区梗死后血管性认知功能损害特点。方法以蒙特利尔认知评估量表(MoCA)为评估工具,检测2011年1月至2012年9月住院的42例基底节内囊区梗死患者起病后3个月(病例组)和35例正常者(对照组)的认知功能状态。结果病例组MoCA分值(18.98±4.36)较对照组(23.17±2.26)明显下降,差异有统计学意义(P<0.01)。病例组中25例(59.5%)MoCA<23分。病例组与对照组比较,视空间与执行(2.90±1.28vs3.69±0.83,P<0.01)、注意力(3.45±1.37vs4.80±1.08,P<0.01)、抽象思维能力(0.76±0.69vs1.31±0.63,P<0.01)均明显下降。结论基底节内囊区梗死后患者血管性认知功能损害发生率高,以执行功能﹑注意力及抽象思维能力损害为主要表现。
Objective To investigate the characteristics of vascular cognitive impairment in basal ganglia after infarction. Methods The MoCA was used to evaluate the efficacy and safety of MoCA during the first three months after onset of disease in the basal ganglia in patients with basal ganglia in hospital from January 2011 to September 2012 (case group) and 35 normal (Control group) cognitive function status. Results The MoCA score (18.98 ± 4.36) in the case group was significantly lower than that in the control group (23.17 ± 2.26), with significant difference (P <0.01). 25 cases (59.5%) in the case group had MoCA <23 points. Compared with the control group, the ability of thinking (0.76 ± 0.69) in attention group (3.90 ± 1.28vs3.69 ± 0.83, P <0.01) was significantly higher than that in control group (3.45 ± 1.37vs4.80 ± 1.08, vs1.31 ± 0.63, P <0.01). Conclusions The incidence of vascular cognitive impairment in patients with basal ganglia infarction is high, and the impairment of executive function, attention and abstract thinking are the main manifestations.