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进一步研究阿霉素及其脂质体在体内的行为,需要灵敏、精确的定量分析方法,本研究建立了适用于微量阿霉素及其脂质体以及其代谢产物Adriamycinol和Adriamycinone在动物组织、血浆及尿中的高效液相分析方法。
Further studies on the behavior of doxorubicin and its liposomes in vivo require a sensitive and accurate quantitative analysis method. In this study, we established a method for the determination of doxorubicin and its liposomes and their metabolites Adriamycinol and Adriamycinone in animal tissues, Plasma and urine of high-performance liquid chromatography method.