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Objective To investigate the biological function of miR-622 in human gastric cancer cell lines of SGC-7901 and NCI-N87 cells and its role in gastric carcinogenesis. Methods We analyzed the expression of miR-622 in those human gastric cancer cell lines by quantitative realtime polymerase chain reaction. Tumorigenesis, migration and invasion ability of miR-622 overexpression was assessed in vitro with miR-622 precursor and inhibitor in in SGC-7901 and NCI-N87 cells. Results The expression level of
Objective To investigate the biological function of miR-622 in human gastric cancer cell lines of SGC-7901 and NCI-N87 cells and its role in gastric carcinogenesis. Methods We analyzed the expression of miR-622 in those human gastric cancer cell lines by quantitative realtime polymerase chain reaction. Tumorigenesis, migration and invasion ability of miR-622 overexpression was assessed in vitro with miR-622 precursor and inhibitor in in SGC-7901 and NCI-N87 cells. Results The expression level of