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甲状腺激素 (TH)在哺乳类动物脑发育中具有重要的作用。孕母亚临床甲状腺功能减退症(甲减 )可造成胎儿神经发育受损 ,对孕妇作甲减筛查是值得推荐的做法。脑TH反应基因的鉴定及功能研究有助于阐明TH调节脑发育的分子机制
Thyroid hormone (TH) plays an important role in mammalian brain development. Clinical hypothyroidism clinical hypothyroidism (hypothyroidism) can cause impaired fetal neurological development, screening for pregnant women hypothyroidism is recommended practice. The identification and functional studies of brain TH response genes help elucidate the molecular mechanisms by which TH regulates brain development