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用肾包膜下移植法将经裸鼠传代的人卵巢癌细胞移植于纯系小鼠Ｃ５７ＢＬ／６和ＢＣＦＩ肾包膜下，观察移植后不同时间移植瘤的大体和病理组织学变化。结果显示：移植瘤体积在术后第６～８天最大，淋巴细胞浸润在８～１２天最严重，瘤细胞在移植后１０天内形态仍完整。同时还比较了两种品系小鼠的差异，为肿瘤免疫学研究提供了一个短期实验的模型。
Human renal ovarian carcinoma cells passaged in nude mice were transplanted under the renal capsule of C57BL / 6 and BCFI mice. The gross and histopathological changes of the transplanted tumor at different time points after transplantation were observed. The results showed that the volume of xenografts was the largest at 6 to 8 days after operation, and the infiltration of lymphocytes was the most severe in 8 to 12 days. The tumor cells remained intact within 10 days after transplantation. At the same time, the differences between the two strains of mice were also compared, which provided a short-term experimental model for tumor immunology research.