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目的通过检测抗苗勒管激素(AMH)在卵巢良性囊肿不同止血方式治疗中的变化,研究其在卵巢功能变化监测中的意义,探讨不同止血方式对卵巢功能的影响。方法选取因卵巢良性囊肿行腹腔镜下卵巢囊肿剥出术的患者90例,其中50例行双极电凝剥离面止血(电凝组),40例行创面缝合止血(缝合组),测定患者术前、术后第2 d、1个月、3个月血清中AMH、卵泡刺激素(FSH)、黄体生成素(LH)和雌二醇(E2)水平。结果电凝组内AMH术前与术后第2 d、1个月比较差异有统计学意义(P<0.05),与术后3个月比较差异无统计学意义(P>0.05);电凝组内FSH、LH及E2术前与术后第2 d、1个月、3个月比较,差异均无统计学意义(P>0.05);缝合组内AMH、FSH、LH及E2术前与术后第2 d、1个月、3个月比较,差异均无统计学意义(P>0.05)。结论 AMH监测卵巢功能变化更可靠、更敏感;不同手术方式对卵巢功能近期有影响。
Objective To investigate the significance of anti-Mullerian hormone (AMH) in the treatment of ovarian benign cyst in different hemostatic ways and to study its significance in the monitoring of ovarian function changes and to explore the effect of different hemostatic methods on ovarian function. Methods Totally 90 patients with ovarian cyst excised due to benign ovarian cyst were selected. Among them, 50 patients underwent bipolar electrocoagulation with peeled surface hemostasis (electrocoagulation group) and 40 patients underwent wound suture hemostasis (suture group) Serum levels of AMH, follicle stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) were measured preoperatively, 2 days, 1 month and 3 months after operation. Results There was no significant difference between preoperative AMH group and the 2nd and 1st month postoperatively in the electrocoagulation group (P <0.05), but no significant difference compared with the 3 month postoperatively (P> 0.05) There was no significant difference in FSH, LH and E2 preoperatively and 2 days, 1 month and 3 months postoperatively between the two groups (P> 0.05) There was no significant difference in the 2nd, 1st, 3rd month after operation (P> 0.05). Conclusion AMH monitoring of ovarian function changes more reliable and more sensitive; different surgical methods have an impact on ovarian function in the near future.