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风湿热(RF)为一种全身性胶原组织的非化脓性炎症,以心脏和关节受累为主,常反复发作,呈急性或慢性经过。大多数患者为儿童和青年,初发者以5~15岁最多见,发病率无明显性别差异。随着链球菌毒力的降低,抗菌素的广泛应用,发病率已下降30%,死亡率减少30~75%,病后头10年的死亡率更降至5%以下。但是本病仍属常见多发病,且RF所引起的永久性心瓣膜损害,是50岁以下患者中最常见的心脏病。
Rheumatic fever (RF) is a non-suppurative inflammation of the generalized collagen tissue that is predominantly involved in the heart and joints and often recurrent and acute or chronic. The majority of patients were children and young people, with initial onset at 5 to 15 years of age and no significant gender differences in morbidity. With the reduction of streptococcal virulence, antibiotics are widely used, the incidence has dropped 30%, the mortality rate decreased 30 ~ 75%, the first 10-year mortality rate even more to 5%. However, the disease is still a common and frequently occurring disease, and permanent heart valve damage caused by RF is the most common heart disease in patients under 50 years of age.