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目的了解共聚焦激光显微内镜(CLE)在慢性胃炎诊断中的操作方法、应用价值及前景。方法应用PENTEXIPK-1000型CLE对17例普通电子内镜下疑诊为慢性胃炎的患者进行激光共聚焦显微内镜检查,对发现病变部位进行共聚焦扫描,并在扫描部位取活检送病理检查,对采集的图像进行描述性分析,并结合活检病理进行对比分析。结果 CLE诊断慢性胃炎,与病理诊断符合率为94.1%。结论 CLE对诊断慢性胃炎具有无创实时的特点,并能发现普通胃镜下未能诊断的病变,导向性活检,尤其对肠上皮化生的敏感性较高。
Objective To understand the operation, application value and prospect of confocal laser microendoscopy (CLE) in the diagnosis of chronic gastritis. Methods PENTEXIPK-1000 CLE was used to detect the pathological changes of the lesions by confocal laser scanning microscopy in 17 patients with suspected chronic gastritis under general electronic endoscopy. The lesions were examined by biopsy and pathological examination , Descriptive analysis of the collected images, and biopsy pathology for comparative analysis. The results of CLE diagnosis of chronic gastritis, consistent with the pathological diagnosis was 94.1%. Conclusion CLE has the characteristics of noninvasive real-time diagnosis of chronic gastritis, and can find uncorrected lesions and guided biopsy under general endoscopy, especially for intestinal metaplasia.