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粒细胞集落刺激因于(thCSF)可引起粒系祖细胞的增殖和分化,因此广泛应用于恶性淋巴瘤或成人T细胞白血病/淋巴瘤(ATL)因强化化疗所致的粒细胞减少症。以往认为thCSF对恶性淋巴瘤细胞没有刺激作用。作者检测重组G-CSF(ffoCSF)对体外原发性ATL细胞生长的刺激作用。方法白
Granulocyte colony stimulating (thCSF) can cause the proliferation and differentiation of granulocyte progenitor cells, so it is widely used in malignant lymphoma or adult T cell leukemia/lymphoma (ATL) due to intensive chemotherapy-induced neutropenia. It has been thought that thCSF has no stimulatory effect on malignant lymphoma cells. The authors examined the stimulatory effect of recombinant G-CSF (ffoCSF) on the growth of primary ATL cells in vitro. Method White