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目的探讨中西结合疗法在原发性痛风急性发作期的应用效果和价值。方法对不能耐受秋水仙碱毒副作用的 2 8例原发性痛风急性发作期患者 ,在去除诱因、严格限制嘌呤饮食的同时 ,予以《升阳益胃汤》为主方的中药治疗 ,视病情佐以西药碱化尿液、控制感染。急性痛风性关节炎控制后 ,加服别嘌呤醇以减少尿酸生成。结果以关节症状、全身症状、血尿酸值为评定标准。 2 8例中可评定疗效者 2 6例 ,显效 10例 (3 8 5 %) ,有效 14例 (5 3 8%) ,无效 2例 (7 7%)。总有效率92 3 %,全组未发现明显毒副的反应。结论中西结合治疗原发性痛风疗效满意 ,尤其对不适合秋水仙碱治疗者 ,可作替代方案。
Objective To explore the effect and value of the combination of Chinese and western medicine in the acute episode of primary gout. Methods 28 cases of primary gout acute exacerbation patients who could not tolerate colchicine toxic side effects were treated with traditional Chinese medicine “Shengyang Yisweitang” as the main prescription while removing the inducer and strictly limiting the purine diet. The condition is accompanied by western medicine urine, control infection. After the control of acute gouty arthritis, plus allopurinol to reduce uric acid formation. The results of joint symptoms, systemic symptoms, serum uric acid value for the evaluation criteria. Twenty-eight of the 28 patients were evaluable for efficacy, 10 (385%) were effective, 14 (53.8%) were effective and 2 (77%) were ineffective. The total effective rate of 92 3%, the whole group did not find significant toxic side reactions. Conclusion The treatment of primary gout with Chinese and western medicine is satisfactory, especially for patients who are not suitable for colchicine treatment.