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目的:为观察雷公藤多甙片伍用小剂量强的松(治疗组35例)治疗肾病综合征的疗效;方法:与常规量激素及/或免疫抑制剂治疗35例为对照组;雷公藤多甙20mg,3次/d;强的松0.7mg/kg.d诱导缓解后渐减量以10~15mg/kg.d维持,疗程6~12个月;结果:治疗组与对照组缓解、有效、无效、总有效率分别为16、14例,12、13例,7、8例,80%、77.1%,两组比较无显著差异p>0.05);但治疗组副作用明显少于对照组;结论:雷公藤多甙伍用小剂量激素治疗肾病综合征疗效较好、副作用较少,是值得进一步试用的方法。
Objective: To observe the efficacy of triptolide tablets in patients with nephrotic syndrome treated with low-dose prednisone (35 cases in treatment group); Methods: 35 cases were treated with conventional hormones and / or immunosuppressive agents as control group; Polyglycoside 20mg, 3 times / d; prednisone 0.7mg / kg. d after induction of remission to reduce the amount of 10 ~ 15mg / kg. d, the course of treatment was 6 to 12 months; Results: The effective rate and the total effective rate of the treatment group and the control group were 16,14 cases, 12,13 cases, 7,8 cases, 80%, 77.1% , No significant difference between the two groups p> 0.05); but the side effects of the treatment group was significantly less than the control group.Conclusion: Tripterygium wilfordii with small doses of hormone treatment of nephrotic syndrome is better, less side effects, is worth further Try it out.