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目的探讨自体血液照射回输提高食管癌患者抗辐射能力及对机体正常组织的合理防护．方法食管癌患者６６例随机分为研究组（自体血液照射回输加放疗）和对照组（常规放疗组）．观察两组急性放射性食管炎的发生率及研究组患者血疗前后ＩＬ２，Ｔ淋巴细胞亚群的变化．结果急性放射性食管炎发生率：研究组为１２１％（４／３３），对照组６０６％（２０／３３，Ｐ＜００１）；发生急性放射性食管炎的平均放疗剂量（Ｘ±ＳｃＧＹ）研究组４０５０±８２２，对照组２４６０±６０９（Ｐ＜００１）；研究组血疗前后ＩＬ２，Ｔ淋巴细胞亚群也都有非常显著变化．结论自体血液照射回输可提高食管癌患者抗辐射功能，可能是低剂量辐射刺激诱发机体的适应性和刺激机体的免疫功能，提高了正常组织对放疗的耐受量而不对肿瘤组织起保护作用．
Objective To investigate the effect of autotransfusion of blood to enhance the radiation resistance of esophageal cancer patients and the reasonable protection of normal tissues. Methods Sixty-six patients with esophageal cancer were randomly divided into study group (autologous blood irradiation and radiotherapy) and control group (conventional radiotherapy group). Observe the incidence of acute radiation esophagitis in both groups and the change of IL 2 and T lymphocyte subsets before and after blood therapy in study group. RESULTS: The incidence of acute radiation esophagitis was 12.1% (4/33) in the study group and 60.6% (20/33, P<0.01) in the control group; the average radiotherapy dose of acute radiation esophagitis (X ±ScGY) The study group was 4050±822, and the control group was 2460±609 (P<001). The IL2 and T lymphocyte subsets also had significant changes before and after blood therapy in the study group. Conclusion Autologous blood irradiation can improve the anti-radiation function of esophageal cancer patients. It may be the low-dose radiation stimulation induced body adaptability and stimulate the body’s immune function, increase the tolerance of normal tissue to radiotherapy without protection of tumor tissue. .