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目的探讨丹红注射液对肾病综合征患者肾血流动力学及血液黏稠状态的影响。方法选取2008年7月～2010年12月于某院进行治疗的64例初发原发肾病综合征患者为研究对象,将其随机分为对照组和观察组各32例,对照组采用泼尼松联合双嘧达莫进行治疗,观察组在对照组的基础上加用丹红注射液进行治疗,后将两组患者治疗前及治疗后4周的肾动脉血流动力学及血液流变学指标进行对比。结果治疗后观察组的肾动脉血流动力学及血液流变学指标的改善幅度均大于对照组,治疗后两组上述检测项目比较,P均﹤0.05,差异均有统计学意义。结论丹红注射液在改善肾病综合征患者肾血流动力学及血液黏稠状态方面均发挥着积极的作用,对于改善肾脏血液循环效果明显。
Objective To investigate the effects of Danhong injection on renal hemodynamics and blood viscosity in patients with nephrotic syndrome. Methods A total of 64 primary primary nephrotic syndrome patients treated in a hospital from July 2008 to December 2010 were selected and randomly divided into control group and observation group of 32 patients. Song combined with dipyridamole for treatment, the observation group on the basis of the control group plus Danhong injection for treatment, the two groups of patients before treatment and after 4 weeks of treatment of renal artery hemodynamics and hemorheology The indicators are compared. Results After treatment, the improvement of renal artery hemodynamics and hemorheology in observation group were greater than that of control group. After treatment, the above two test items were compared, P <0.05, the difference was statistically significant. Conclusion Danhong injection has a positive effect on improving renal hemodynamics and blood viscosity in patients with nephrotic syndrome, and has an obvious effect on improving renal blood circulation.