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已经报道,睾丸生精障碍是以界膜为靶区(targetarea),以间质细胞和支持细胞为靶细胞(targetcell),以线粒体为靶点(target point)的生理与病理的发病过程,而线粒体又是中心环节和关键部位,为此,再就线粒体缺失与不育症予以综述。一、线粒体与精子凋亡精子凋亡与男性不育症关系密切,但精子凋亡率参考值由于方法不同差异较大。岳焕勋报告,对34份年龄为33.5岁的检精者采用荧光显微图像测定凋亡精子,精液中凋亡精子百分率为6.5%,最大值20.1%,最小值1.3%;坏死精子为11.8%,最大值30.6%,最小值3.4%。周增娣等采用AnnexinV荧光染色流式细胞技术检测精液精子凋亡率为
It has been reported that testicular spermatogenic disorders are the pathophysiological and pathological processes that target the mitochondria with target cells and target cells in the target membrane, Mitochondria are the central part and the key part. Therefore, we reviewed mitochondria and infertility. First, mitochondria and sperm apoptosis Sperm apoptosis and male infertility are closely related, but the reference rate of sperm apoptosis due to different methods are different. Yue Huanxun report, 34 33.5-year-old semen were apoptotic sperm fluorescence microscopy image, the percentage of apoptotic sperm in the sperm was 6.5%, the maximum value of 20.1%, the minimum value of 1.3%; necrotic sperm was 11.8% The maximum value is 30.6% and the minimum value is 3.4%. Zhouzeng Di and other using AnnexinV fluorescence staining flow cytometry sperm apoptosis rate was