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本文对243例复治肺结核及97例初治肺结核耐药的研究结果表明,复治肺结核患者的耐药发生率明显高于初治肺结核患者,两者之间有极显著性差异(P<0.01)。复治耐2种药以上274例(97.18％),初治耐2种药以上52例(53.61％),复治以耐INH为首位,初治以耐SM为首位。无论初、复治对H、R、E、S耐药率均较高,原发耐药率为74.23％,继发耐药率为97.53％,是临床上治疗失败的主要原因之一。
In this paper, 243 cases of re-treatment of pulmonary tuberculosis and 97 cases of untreated tuberculosis drug resistance results show that re-treatment of tuberculosis patients with drug resistance was significantly higher than those of newly diagnosed tuberculosis patients, there was a significant difference between the two (P <0.01 ). 274 (97.18%) were resistant to more than 2 kinds of drugs, 52 cases (53.61%) were more than 2 kinds of drugs, retreatment was first to be resistant to INH, and first to SM was the first. Both initial and retreatment of H, R, E, S resistance rates were high, the primary resistance rate of 74.23%, the secondary resistance rate of 97.53%, is one of the main clinical failure.