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目的研究卡前列素氨丁三醇(欣母沛)预防和治疗产后出血的临床疗效。方法将150例产后出血高危产妇分为缩宫素组和欣母沛组(缩宫素+欣母沛)各75例,比较两组第三产程时间、术后出血情况及不良反应事件。结果欣母沛组第三产程时间,术后2h、24h出血量、产后出血率6.7%均明显低于缩宫素组(P<0.05)。缩宫素组无不良反应发生,欣母沛组共发生25例,占33.3%。结论欣母沛联合缩宫素能够发挥更强的促进宫缩、预防产后出血作用,临床价值重大。
Objective To study the clinical efficacy of carboprost trometamol (Yan Xin Pei Pei) in the prevention and treatment of postpartum hemorrhage. Methods A total of 150 high risk pregnant women with postpartum hemorrhage were divided into three groups: oxytocin group and Xinmianpei group (oxytocin + Xinmaopei). The time of the third stage of labor, postoperative bleeding and adverse reaction events were compared between the two groups. Results The time of the third stage of labor, the amount of bleeding after 2h and 24h, the rate of postpartum hemorrhage 6.7% were significantly lower than those of oxytocin group (P <0.05). Oxytocin group no adverse reactions occurred, Xin Yan Pei group occurred in 25 cases, accounting for 33.3%. Conclusions Xin Maopei oxytocin combined with oxytocin can play a stronger role in promoting uterine contractions, prevention of postpartum hemorrhage, the clinical value.