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口腔鳞癌是口腔中常见的恶性肿瘤，一系列研究表明，它的发生发展和癌基因与抑癌基因的异常表达有关。其中最为常见的为P53和近年来发现的P16（CDKNZ／INK4A）基因。P53基因和多种肿瘤有关。工常情况下介导了“细胞凋亡”，当其发生突变，则丧失这种作用，促发肿瘤的形成［‘J?
Oral squamous cell carcinoma is a common malignant tumor in oral cavity. A series of researches have shown that it is related to the occurrence and development of cancerous and overexpressing oncogenes and tumor suppressor genes. The most common one is P53 and the P16 (CDKNZ / INK4A) gene found in recent years. P53 gene and a variety of tumors. Under normal circumstances workers often mediate “apoptosis”, when its mutation, the loss of this effect, promote the formation of tumors ['J?