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目的 探讨2型糖尿病患者自主神经功能状态及其临床意义。方法 采用24h动态心电图心率变异性(HRV)时域和频域,对44例2型糖尿病患者与30例健康对照者进行比较分析。结果 糖尿病患者HRV时域和频域的9项指标比对照组显著降低。糖尿病患者随病程延长HRV指标有降低的趋势。结论 提示2型糖尿病患者植物神经功能有损害,HRV的时域和频域指标分析能评估和反映其受损状况。
Objective To investigate the functional status of autonomic nerve in type 2 diabetic patients and its clinical significance. Methods Twenty-four patients with type 2 diabetes mellitus and 30 healthy controls were analyzed by HRV time domain and frequency domain. Results Nine indicators of HRV in time and frequency domain of HRV were significantly lower than those in control group. Diabetic patients with the duration of HRV indicators have decreased. Conclusions The autonomic dysfunction of patients with type 2 diabetes mellitus is impaired. Time and frequency domain analysis of HRV can assess and reflect the damage status.