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目的探讨多索茶碱(DL)和氨茶碱(AL)在治疗支气管哮喘(BA)中的应用。方法 240例BA患者,将其分为三组,每组80例,用DL联合丙酸氟替卡松(FP)治疗Ⅰ组的BA患者,用AL结合FP治疗Ⅱ组的BA患者,用FP单一治疗Ⅲ组的BA患者,比较其疗效。结果Ⅰ组的总有效率为96.3%、Ⅱ组的总有效率为82.5%,Ⅲ组的总有效率为62.5%,Ⅰ、Ⅱ组的总有效率高于Ⅲ组,差异有统计学意义(P<0.05),而Ⅰ组的总有效率高于Ⅱ组,差异有统计学意义(P<0.05)。结论结合茶碱药物治疗BA的效果较单一FP治疗效果显著,临床上合理使用茶碱类药物能有效治疗BA,其中合理使用多索茶碱对BA进行治疗效果更佳。
Objective To investigate the application of doxofylline (DL) and aminophylline (AL) in the treatment of bronchial asthma (BA). Methods A total of 240 patients with BA were divided into three groups of 80 cases. Patients in group BA with DL combined with fluticasone propionate (FP) Group of patients with BA, compared its efficacy. Results The total effective rate of group Ⅰ was 96.3%, the total effective rate of group Ⅱ was 82.5%, the total effective rate of group Ⅲ was 62.5%, the total effective rate of group Ⅰ and Ⅱ was higher than that of group Ⅲ, the difference was statistically significant ( P <0.05), while the total effective rate of group Ⅰ was higher than that of group Ⅱ, the difference was statistically significant (P0.05). Conclusion The combination of theophylline treatment of BA than the effect of a single significant effect of FP, the rational use of theophylline clinically effective treatment of BA, including the rational use of doxofylline BA treatment is better.