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洋地黄类药物中毒所致的心律失常,有时常用的治疗方法难以快速奏效。近年来有报道应用地高辛特异性抗原结合碎片对威胁生命的洋地黄类中毒病人的治疗、具有十分满意的效果。本文重点介绍2例地高辛特异性抗体碎片纠正地高辛毒性的神奇效果和所需的时间。2例均因自杀吞服地高辛(0.25mg/片)各100片后,分别经2至数h出现恶心、呕吐,心电图证实1例为30次/min(曾现短阵交界性逸搏心律和逸搏、伴高血钾为7.3mmol/L)1例为35次/min严重窦缓,血清地高辛浓度各为21μg/ml和16.6μg/ml。经快速
Digitalis poisoning caused by arrhythmia, sometimes used in the treatment is difficult to quickly work. In recent years, it has been reported that the application of digoxin-specific antigen-binding fragments to the treatment of life-threatening digitalis patients has been very satisfactory. This article highlights the magical effects and the time required to correct digoxin toxicity in two digoxin-specific antibody fragments. 2 cases were swallowed by suicide digoxin (0.25mg / tablet) of 100 tablets, respectively, after 2 to several hours of nausea, vomiting, electrocardiogram confirmed 1 case was 30 beats / min (there was a borderline escape rhythm And Yat stroke with hyperkalemia of 7.3 mmol / L). One case was severe sinus rhythm of 35 times / min and serum digoxin concentration was 21 μg / ml and 16.6 μg / ml respectively. Fast