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Objective.-To compare the mode of delivery in two groups of patients selected by their response after induction of labour with mifepristone.Patien ts and methods.-We studied retrospectively 89cases of labour induction with viable children after 41weeks of gestation.Bishop scores were less than 6.Patients were given200mg of mifepris-tone per day for 48h.They were retrospectively divided into group 1(spontaneous onset of labour or prema ture rupture of membranes before the thir d day)and group 2(not in labour by that date).Results.-The mean Bishop score at inclusion was 3.1±1.3.Amon g the 51patients(53.9%)in group 1,one required prostagland ins andwe performed 10cesarean sections.In g roup 2,the mean Bishop score at the 3rd day was 4.4±1.3(P<0.0001).Twenty -four patients required prostaglandins(P<0.0001)andwe performed 17cesarean section s(P =0.01).The number of cesarean sections increased with the dose of prostaglandins(P =0.025).We observed no maternal or fetal complications.Discussion an d conclusions.-Mifepristone was successful in inducing labour sponta-neously in over 50%of pregnancies after 41weeks of gestation.In the other group,the pr obability of vaginal delivery was reduced especially when high doses of prostaglandinswere required.Afte r the use of mifepristone,we suggest to shorten the duration of prostaglandin admin-istration(two applications of 2mg dinoproston e)before performing cesarean section.
Objective-To compare the mode of delivery in two groups of patients selected by their response after induction of labor with mifepristone. Patien ts and methods. -We studied retrospectively 89cases of labor induction with viable children after 41 weeks of gestation. Bishop scores were less than 6. Patients were given 200 mg of mifepris-tone per day for 48 h. They were retrospectively divided into group 1 (spontaneous onset of labor or prema ture rupture of membranes before the thir d day) and group 2 (not in labor by that date) . Results - The mean Bishop score at inclusion was 3.1 ± 1.3. Amon g the 51 patients (53.9%) in group 1, one required prostagland ins and we performed 10cesarean sections. In g roup 2, the mean Bishop score at the 3rd day was 4.4 ± 1.3 (P <0.0001). Twenty-four patients required prostaglandins (P <0.0001) and We performed 17ces section section (P = 0.01). The number of cesarean sections increased with the dose of prostaglandins no maternal or fetal complications. Discussi on an d conclusions. -Mifepristone was successful in inducing labor sponta-neously in over 50% of pregnancies after 41 weeks of gestation. the other group, the pr obability of vaginal delivery was reduced especially when high doses of prostaglandinswere required .Afte r the use of mifepristone, we suggest to shorten the duration of prostaglandin admin-istration (two applications of 2mg dinoproston e) before performing cesarean section.