肝内胆汁淤积(introhepatic cholestasis,IC)是指肝细胞和(或)毛细胆管胆汁分泌障碍,导致胆汁的生成障碍以及流动停滞或受抑,使正常分泌到胆汁中的物质积于肝内和血清内,胆汁流入十二指肠减少或消失。黄疸和皮肤瘙痒是肝内胆汁淤积的主要临床表现。或可出现黄色瘤、吸收不良和 Introhepatic cholestasis (IC) refers to the disorder of bile secretion in hepatocytes and / or the bile ducts resulting in the formation of bile and the stagnation or suppression of flow. The substance normally secreted into the bile accumulates in the liver and serum Within the bile flow into the duodenum to reduce or disappear. Jaundice and pruritus are the main clinical manifestations of intrahepatic cholestasis. Or there may be yellow tumor, malabsorption and