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目的研究氨哮素(克仑特罗)微型灌肠剂的生物利用度.方法 比较在家兔体内微型灌肠剂和栓剂的区别.结果通过AUC_(0-1)的比较发现微型灌肠剂的体内吸收量高于栓剂.结论 氨哮素(克仑特罗)微型灌肠剂是临床可应用的制剂.
OBJECTIVE To study the bioavailability of minocycline (Clenbuterol) mini enema.Methods The difference between mini-enema and suppository in rabbits was compared.Results The in vivo absorption of mini-enema was found by comparison of AUC 0-1 Higher than the suppository.Conclusion Aminocetin (Clenbuterol) micro enema is a clinically applicable preparation.