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目的:观察安肠止痛汤结合西药治疗腹泻型肠易激综合征的临床疗效。方法 :将90例患者随机分为2组,对照组45例予西药常规治疗,观察组在对照组基础上加用安肠止痛汤治疗,观察治疗前后中医症状评分、肠易激综合征特异性生活质量量表(IBS-QOL)和生活质量评分(SF-36),评价2组临床疗效。结果:总有效率观察组为91.11%,对照组为71.11%,2组比较,差异有统计学意义(P<0.05)。治疗后观察组腹部不适症状、腹胀、大便次数、大便性质等评分均低于对照组,差异有统计学意义(P<0.05)。治疗后2组IBS-QOL评分较治疗前降低,SF-36评分较治疗前升高,差异均有统计学意义(P<0.05);治疗组上述指标改善较对照组更显著(P<0.05)。结论:安肠止痛汤结合西药治疗腹泻型肠易激综合征,可有效缓解腹胀、排便紧迫感、腹泻等症状,有利于提高临床疗效。
Objective: To observe the clinical effect of Anchang Zhitong Decoction combined with Western medicine in treating diarrhea-predominant irritable bowel syndrome. Methods: 90 patients were randomly divided into two groups, the control group of 45 cases of Western medicine routine treatment, the observation group in the control group based on the use of Anchang Zhitong Tang treatment, before and after treatment of Chinese medicine symptoms score, irritable bowel syndrome specific Quality of Life Scale (IBS-QOL) and Quality of Life Scale (SF-36) were used to evaluate the clinical efficacy of the two groups. Results: The total effective rate was 91.11% in the observation group and 71.11% in the control group. There was significant difference between the two groups (P <0.05). The scores of abdominal discomfort, bloating, stool frequency and stool nature in the observation group after treatment were all lower than those in the control group (P <0.05). After treatment, IBS-QOL scores of two groups were lower than those before treatment, and SF-36 scores were higher than before treatment (P <0.05). The improvement of the above parameters in the treatment group was more significant than that in the control group (P <0.05) . Conclusion: Combination of Anchang Zhitong Decoction with western medicine in treating diarrhea-predominant irritable bowel syndrome can effectively relieve the symptoms of abdominal distension, urgency of bowel movement and diarrhea, which is helpful to improve the clinical curative effect.