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目的调查十堰市郧阳区轮状病毒(RV)感染致腹泻患儿体质量指数(BMI)及身高分布情况。方法选取腹泻患儿的1 100份粪便标本,通过面对面交流或问卷调查的方式了解腹泻患儿流行病学特点,通过ELISA测定粪便标本中的RV抗原(A组),统计A组RV抗原阳性率,分析不同性别、年龄、发病时间儿童A组RV抗原阳性率。以A组RV感染致腹泻患儿为观察组,选择非RV感染腹泻患儿100例、健康儿童100例分别为对照组、正常组,比较各组儿童乳糖不耐受率、身高、体重及BMI。结果 1 100份标本中,检出A组RV抗原阳性372例(33.82%)。男童A组RV抗原阳性率明显高于女童(P<0.05)。6~12个月与3~5岁(不含3岁和5岁)儿童A组RV抗原阳性率比较差异有统计学意义(P<0.05)。11月A组RV抗原阳性率最高(78.43%),其次是1月(78.26%),6月A组RV抗原阳性率(11.86%)最低。观察组、对照组患儿乳糖不耐受率均明显高于正常组(P<0.05)。观察组与对照组儿童乳糖不耐受率比较差异无统计学意义(P>0.05)。3组儿童身高、体重比较差异均无统计学意义(P>0.05);3组儿童BMI比较差异有统计学意义(P<0.05)。观察组、对照组患儿体重、BMI均明显低于正常组,差异均有统计学意义(P<0.05)。结论 A组RV是导致<5岁患儿腹泻的主要病原体之一,特别是6~12个月的婴幼儿,且好发于秋、冬季;A组RV感染致腹泻患儿乳糖不耐受率较高,腹泻时间越长,乳糖不耐受率越高,对患儿体重、BMI造成一定的影响,而对其身高无影响。
Objective To investigate the body mass index (BMI) and height distribution of children with diarrhea caused by rotavirus (RV) infection in Yunyang District of Shiyan City. Methods A total of 1,100 stool specimens from children with diarrhea were collected. The epidemiological characteristics of children with diarrhea were analyzed by face-to-face communication or questionnaire survey. The RV antigen in stool samples was measured by ELISA (group A). The positive rate of RV antigen in group A , Analysis of different gender, age, onset time group A RV antigen positive rate. A group of children with RV-induced diarrhea was selected as the observation group. 100 children with non-RV-infected diarrhea and 100 healthy children were selected as control group, normal group, lactate intolerance rate, height, body weight and BMI . Results Of the 100 samples, 372 (33.82%) were positive for RV antigen in group A. The positive rate of RV antigen in group A was significantly higher than that in girls (P <0.05). The positive rate of RV antigen in children aged 6 to 12 months and 3 to 5 years (excluding 3 and 5 years old) was significantly different (P <0.05). The positive rate of RV antigen in group A was the highest (78.43%) in November, followed by January (78.26%). The positive rate of RV antigen in group A was the lowest (11.86%) in June. The rates of lactose intolerance in observation group and control group were significantly higher than those in normal group (P <0.05). There was no significant difference in lactose intolerance between observation group and control group (P> 0.05). There was no significant difference in height and weight between the three groups (P> 0.05). There was significant difference in BMI between the three groups (P <0.05). The body weight and BMI of the observation group and the control group were significantly lower than those of the normal group (P <0.05). Conclusion RV in group A is one of the major pathogens causing diarrhea in children <5 years of age, especially in infants and young children aged 6 to 12 months, and occurs in autumn and winter. In group A, the rate of lactose intolerance in children with diarrhea due to RV infection Higher, longer diarrhea, lactose intolerance rate of children with weight, BMI have a certain impact, but no effect on their height.