论文部分内容阅读
目的对比实时三维超声心动图(RT-3DE)与组织多普勒(TDI)评价扩张型心肌病(DCM)患者的左心室收缩功能的临床意义。方法对临床及超声心动图确诊为DCM患者33例,其中男性20例,女性13例;年龄45~69岁,平均年龄53岁;符合1996年世界卫生组织(WHO)对DCM的诊断标准,均为窦性心律,纽约心脏学会(NYHA)分级Ⅱ~Ⅳ级。健康对照组28例,其中男性16例,女性12例;年龄43~64岁,平均年龄51岁;体格检查、心电图及超声心动图证实无心血管疾病,均为窦性心律。分别行二维超声心动图(2DE)、RT-3DE及TDI扫查,测量并计算各参数,以28例健康体检者作为对照。结果 DCM患者左心室射血分数(LVEFSimpson与LVEFRT-3DE)、Sm明显减低,Tei指数增大,与对照组相比,差异均存在显著统计学意义(P<0.01)。对照组中,LVEFRT-3DE、Tei指数及Sm与LVEFSimpson有显著相关性(分别为r=0.895,P<0.01;r=0.629,P<0.05;r=-0.760,P<0.05),在DCM患者中,LVEFRT-3DE与LVEFSimpson相关性仍然显著(r=0.818,P<0.01),LVEFRT-3DE与Tei指数及Sm的相关性较对照组要明显减低(分别为r=0.487,P<0.05;r=-0.493,P<0.05)。结论 RT-3DE较Sm、Tei指数更能有效评价DCM患者左心室收缩功能,为临床提供有价值的信息。
Objective To compare the clinical significance of left ventricular systolic function in patients with dilated cardiomyopathy (DCM) by real-time three-dimensional echocardiography (RT-3DE) and tissue Doppler (TDI). Methods The clinical and echocardiographic diagnosis of DCM in 33 patients, including 20 males and 13 females; aged 45 to 69 years, mean age 53 years; in line with the 1996 World Health Organization (WHO) on the diagnosis of DCM, were For sinus rhythm, New York Heart Association (NYHA) grade Ⅱ ~ Ⅳ grade. Healthy control group of 28 cases, including 16 males and 12 females; aged 43 to 64 years, mean age 51 years; physical examination, electrocardiogram and echocardiography confirmed no cardiovascular disease, are sinus rhythm. Two-dimensional echocardiography (2DE), RT-3DE and TDI scanning were performed respectively, and the parameters were measured and calculated. Twenty-eight healthy subjects were used as control. Results Compared with control group, the left ventricular ejection fraction (LVEFSimpson and LVEFRT-3DE), Sm decreased significantly and Tei index increased in DCM patients (P <0.01). In the control group, LVEFRT-3DE, Tei index and Sm were significantly correlated with LVEFSimpson (r = 0.895, P <0.01; r = 0.629, P < , The correlation between LVEFRT-3DE and Tei index and Sm was significantly lower than that of the control group (r = 0.487, P <0.05, respectively; r = -0.493, P <0.05). Conclusion RT-3DE is more effective than Sm and Tei index in evaluating left ventricular systolic function in patients with DCM, providing valuable information for clinic.