论文部分内容阅读
[目的]分析恶性血液病并发侵袭性真菌感染(IFI)的临床特点,探讨有效地治疗方法。[方法]对患者的临床资料包括临床表现、致病菌、感染部位和疗效等进行分析。[结果]致病菌以念珠菌为主,感染部位以呼吸道感染为主;治疗总有效率为60%,氟康唑组有效率为37.5%,伊曲康唑组有效率为58.3%,卡泊芬净组有效率为70%。[结论]对恶性血液病并发侵袭性真菌感染可疑患者应及时进行经验性抗生素治疗,卡泊芬净抗菌谱广,对IFI的治疗效果好。
[Objective] To analyze the clinical features of malignant hematological disease complicated with invasive fungal infection (IFI) and discuss the effective treatment methods. [Methods] The clinical data of patients, including clinical manifestations, pathogens, infection sites and efficacy were analyzed. [Results] The main pathogenic bacteria were Candida albicans. The main infection area was respiratory tract infection. The total effective rate was 60%, the effective rate was 37.5% in fluconazole group and 58.3% in itraconazole group Po Fen net group effective rate of 70%. [Conclusions] Empiric antibiotic treatment should be conducted in patients with suspected hematologic malignancy complicated with invasive fungal infection. Caspofungin has broad antimicrobial spectrum and good therapeutic effect on IFI.