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目的研究山苍子油对小鼠系统性白念珠菌感染的治疗作用。方法建立小鼠系统性白念珠菌感染模型,观察给药后小鼠中位生存时间,并检测给药后小鼠肾脏菌落形成单位计数。结果山苍子油能明显延长小鼠的中位生存时间,降低肾脏菌落形成单位计数。结论山苍子油对小鼠系统性白念珠菌感染具有治疗作用,值得进一步研究和开发。
Objective To study the therapeutic effect of Litsea Cubeba oil on systemic Candida albicans infection in mice. Methods A mouse model of systemic Candida albicans infection was established. The median survival time of mice after administration was observed, and the number of kidney colony forming units was measured after administration. Results Litsea cubeba oil could significantly prolong the median survival time of mice and reduce the number of kidney colony forming units. Conclusion Litsea cubeba oil has curative effect on systemic Candida albicans infection in mice, and it is worth further research and development.