脱发作为二期梅毒的一种症状，临床上并非少见，但却易被临床医师忽略，我们报道近 5年来以脱发为主诉就诊的二期梅毒 28例。 一、临床资料 28例患者均以脱发为主诉就诊于皮肤科门诊，其中男 21例，女 7例，年龄 20～ 45岁，自发现脱发到就诊时间从 1周到 2个多月不等。首诊 Hair loss as a symptom of secondary syphilis is clinically not uncommon, but it is easy to be overlooked by clinicians, we report in the past 5 years to hair loss-based treatment of secondary syphilis in 28 cases. First, the clinical data of 28 patients were mainly treated with alopecia in dermatology clinic, including 21 males and 7 females, aged 20 to 45 years old, since the discovery of hair loss to treatment time ranging from 1 week to more than 2 months. First visit