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本研究的目的是通过主观听阈和耳蜗电图的检查手段,评价美尼尔氏病患者静脉注入乙酰唑胺的即时作用。乙酰唑胺即Diamox,是水溶性磺基酰胺衍化物,对广泛分布的碳酸酐酶有特殊抑制作用。作者选择30例美尼尔氏病患者,其中10例为双侧性,23例病变处于早期波动阶段,有8例曾作过内淋巴囊手术,仅3例治好,因此27例为活动期。对照组10例,7例为不同原因的感音性聋,1例为病因不明的双耳感音性聋,2例听力
The purpose of this study was to evaluate the immediate effect of intravenous acetazolamide in patients with Meniere’s disease through subjective and auditory cochlear electrograms. Acetazolamide, Diamox, is a water-soluble sulfamide derivative that has a specific inhibitory effect on widely distributed carbonic anhydrases. The authors selected 30 patients with Meniere’s disease, of which 10 were bilateral and 23 were in early phase of the disease. Eight patients had undergone endolymphatic sac surgery and only three had healed, and 27 were active . Control group, 10 cases, 7 cases for different causes of sensorineural hearing loss, 1 case of unknown etiology of bilateral ear hearing loss, 2 cases of hearing