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目的:研究硫糖铝混悬液对消化性溃疡的疗效。方法:74例经胃镜证实的活动性消化性溃疡病人,其中51例十二指肠球部溃疡和23例胃溃疡,服用硫糖铝混悬液5mL(含1.0g),饭前,qid,各4wk和6wk为一个疗程。另25例消化性溃疡病人,其中17例十二指肠溃疡和8例胃溃疡病人,服用硫糖铝片剂,1.0g,饭前,qid,作为对照组。结果:治疗组十二指肠球部溃疡与胃溃疡总显效率分别为90%和87%。对照组分别为53%和50%(P<0.05)。结论:硫糖铝混悬液对消化性溃疡有明显治疗作用。
Objective: To study the effect of sucralfate suspension on peptic ulcer. Methods: Seventy-four patients with active peptic ulcer confirmed by gastroscope, including 51 cases of duodenal ulcer and 23 cases of gastric ulcer, were treated with sucralfate suspension 5mL (1.0g), pre-qid , 4wk and 6wk for a course of treatment. Another 25 cases of peptic ulcer patients, of which 17 cases of duodenal ulcer and 8 cases of gastric ulcer patients, taking sucralfate tablets, 1.0g, before meals, qid, as a control group. Results: The total effective rates of duodenal ulcer and gastric ulcer in treatment group were 90% and 87% respectively. The control group was 53% and 50% (P <0.05). CONCLUSIONS: Sucralfate suspensions have a significant therapeutic effect on peptic ulcer disease.