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目的:对盐酸氨溴索联合氨茶碱应用于慢性喘息型支气管炎急性发作治疗中的临床疗效进行观察。方法:选取于2014年3月至2015年9月该院收治的慢性喘息型支气管炎急性发作患者75例,并随机分为参照组(35例)和治疗组(40例),在常规治疗的基础上前者给予盐酸氨溴索治疗,后者给予盐酸氨溴索联合氨茶碱治疗。结果:治疗组患者的显效率为74.4%,治疗总有效率为92.3%,均显著高于参照组的41.7%和72.2%;同时,治疗组患者的PaO_2显著高于参照组,PaCO_2显著低于参照组,组间差异经t检验,有统计学意义(P<0.05)。结论:盐酸氨溴索联合氨茶碱应用于慢性喘息型支气管炎急性发作治疗中的临床疗效确切,能够使患者的临床症状迅速缓解,值得大力推广。
Objective: To observe the clinical efficacy of ambroxol combined with aminophylline in the treatment of acute asthmatic bronchitis. Methods: Seventy-five patients with acute asthmatic bronchitis admitted from March 2014 to September 2015 in our hospital were randomly divided into control group (35 cases) and treatment group (40 cases) On the basis of the former given ambroxol hydrochloride treatment, the latter given ambroxol hydrochloride combined with aminophylline treatment. Results: The effective rate of treatment group was 74.4%, and the total effective rate was 92.3%, which was significantly higher than that of reference group (41.7% and 72.2%). Meanwhile, PaO_2 of treatment group was significantly higher than that of reference group and PaCO_2 was significantly lower than that of reference group The reference group, the differences between groups by t test, with statistical significance (P <0.05). Conclusion: The clinical efficacy of ambroxol combined with aminophylline in acute episode of chronic asthmatic bronchitis is definite, and the clinical symptoms of the patients can be quickly relieved, which is worth to be promoted.