Schmid及其同事所创立的微核试验,在活体检测致突变物的染色体断裂作用中,是一种比较简易而又快速的方法;同时对于检测化学物质的细胞毒性和细胞周期专一致突变性,也能提供有用的资料,因此在有关研究中已得到广泛应用。但该试验涂片染色需重复三次,且细胞色彩易变,使检验者有时不易鉴别。同时,近来虽对微核试验的技术方法有 The micronucleus test set up by Schmid and co-workers is a relatively simple and rapid method for detecting the chromosomal cleavage of mutants in vivo. In addition, to detect cytotoxicity and cell-cycle-specific mutagenicity of chemical substances, Also can provide useful information, so in the relevant research has been widely used. However, the test smear staining to be repeated three times, and cell color variable, so that the examiner is sometimes not easy to identify. In the meantime, although the technical methods of micronucleus test have been introduced recently