以镍－铝（Ｎｉ－Ａｌ）合金碱性重水溶液为还原体系，研究了多种相转移催化剂对氘代苯乙酮－ｄ８还原反应的影响，探讨了有关相转移催化作用机理．实验发现，以适量聚乙二醇３００（或４００）、β－环糊精及二苯并－１８－冠－６作相转移催化剂时，还原效率较高，产物氘代１－苯基乙醇－ｄ１０的产率可达９０％以上． The effects of various phase transfer catalysts on the reduction of deuterated acetophenone-d8 were studied by using alkaline heavy aqueous solution of nickel-aluminum alloy (Ni-Al) as reduction system. The mechanism of phase transfer catalysis was also discussed. The experimental results showed that the reductive efficiency was high when using appropriate amount of polyethylene glycol 300 (or 400), β-cyclodextrin and dibenzo-18-crown-6 as the phase transfer catalyst. The product deuterated 1-phenylethanol- d10 yield up to 90% or more.