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作为慢性消化系统疾病中常见的致病菌,幽门螺旋杆菌(Helicobacter pylori,HP)是一种寄生于胃黏膜的革兰氏阴性菌株,可以导致多种胃部疾病,如胃炎、胃溃疡,严重者导致胃癌。目前常用的治疗HP的方法是胃黏膜保护剂、质子泵抑制剂和抗生素联合疗法(三联疗法),但近些年来HP的耐药性显著增加,三联疗法的治疗效果显著降低~([1,2])。因此需要寻找更有效的抗生素药物组合治疗方案。本研究应用诺氟沙星联合三联疗法治疗HP相关性胃溃疡,对比
As a common pathogen in chronic digestive diseases, Helicobacter pylori (HP), a gram-negative strain that colonizes the gastric mucosa, can cause a variety of stomach disorders such as gastritis, gastric ulcer, severe Cause stomach cancer. Currently used in the treatment of HP is the gastric mucosal protective agent, proton pump inhibitor and antibiotic combination therapy (triple therapy), but in recent years, the drug resistance of HP increased significantly, the triple therapy significantly reduced the therapeutic effect of ~ ([1, 2]). Therefore, there is a need to find a more effective antibiotic drug combination regimen. In this study, norfloxacin combined with triple therapy for HP-associated gastric ulcer, compared