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目的探讨福辛普利联合丹红注射液治疗早期糖尿病肾病的临床疗效。方法回顾性分析方城县人民医院2011年8月至2012年8月122例早期糖尿病肾病的临床资料,随机将其分为观察组和对照组,两组均给予常规治疗,对照组给予福辛普利,观察组给予福辛普利联合丹红注射液;观察两组血脂血糖及肾功能等变化。结果观察组血脂变化与对照组相比,差异无统计学意义(P>0.05);与治疗前相比较,差异有统计学意义(P<0.05)。观察组肾功能与对照组相比,差异有统计学意义(P<0.05)。结论福辛普利联合丹红注射液治疗早期糖尿病肾病临床疗效显著,能改变早期肾功能,值得临床推广。
Objective To investigate the clinical efficacy of fosinopril combined with Danhong injection in the treatment of early diabetic nephropathy. Methods The clinical data of 122 cases of early diabetic nephropathy in Fangcheng County People’s Hospital from August 2011 to August 2012 were retrospectively analyzed. The patients were randomly divided into observation group and control group. Both groups were given conventional treatment. The control group was given Fusin Puli, observation group were given fosinopril combined Danhong injection; observed blood lipid and blood glucose and renal function changes. Results Compared with the control group, there was no significant difference in the change of blood lipid between the observation group and the control group (P> 0.05). The difference was statistically significant (P <0.05) compared with that before treatment. The renal function of the observation group compared with the control group, the difference was statistically significant (P <0.05). Conclusion Fosinopril combined with Danhong injection in the treatment of early diabetic nephropathy significant clinical effect, can change the early renal function, deserved clinical promotion.