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除松果腺分泌褪黑素 (MT)外 ,胃肠道组织也能分泌MT ,且其分泌与进食和营养成份有关。胃肠道组织有广泛分布的MT结合位点 ,其密度较高 ,部位多是结肠、回肠、盲肠和阑尾。胃肠道组织分泌MT ,以回肠末端为甚。MT有保护胃粘膜、增加胃粘膜血流量、清除氧自由基等作用 ,可抑制溃疡的发生和发展。MT还可调节回 盲 结肠的肌电活动 ,导致胃肠运动加快 ,并可协调胆囊收缩素 (CCK)的促结肠运动功能 ,其机制与拮抗 5 HT的作用有关。MT亦能减轻化学致癌物的致癌作用 ,促进Aloe的抗癌作用。
In addition to pineal gland secretion of melatonin (MT), gastrointestinal tissue can also secrete MT, and its secretion and eating and nutrition related. Gastrointestinal tissue has a broad distribution of MT binding sites, the higher density, the site is mostly colon, ileum, cecum and appendix. Gastrointestinal tissue secretion of MT, to the terminal ileum even. MT has protective gastric mucosa, increased gastric mucosal blood flow, scavenging oxygen free radicals and other effects, can inhibit the occurrence and development of ulcers. MT can also regulate the myoelectric activity of the ileocecal colon, leading to accelerated gastrointestinal motility and coordinating the promoting of colonic motility of cholecystokinin (CCK), the mechanism of which is related to the antagonism of 5HT. MT can also reduce the carcinogenic effects of chemical carcinogens and promote Aloe’s anti-cancer effect.