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在美国 ,糖尿病肾病 (ｄｉａｂｅｔｉｃｎｅｐｈｒｏｐａｔｈｙ ,ＤＮ)已超过高血压性肾硬化成为导致终末期肾病 (ｅｎｄ ｓｔａｇｅｒｅｎａｌｄｉｓｅａｓｅ ,ＥＳＲＤ)的第一大主要原因[1] 。近4 0 %的ＥＳＲＤ患者伴有ＤＮ ,其中约 90 %患有非胰岛素依赖型糖尿病 (ｎｏｎｉ
Diabetic nephropathy (DN) has surpassed hypertensive nephrosclerosis as the leading cause of end stage renal disease (ESRD) in the United States [1]. Nearly 40% of patients with ESRD have DN, of which about 90% have non-insulin-dependent diabetes (noni