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利用等位基因特异扩增法(ASA)为基础的基因分型法,对细胞色素P4502D6(CYP2D6)缺陷型等位基因携带者的9个家庭共38人进行了基因分型,并与用右旋美沙芬为探针的表型分型法进行对比,发现两种方法的结果是一致的,CYP2D6酶缺陷型等位基因呈常染色体隐性遗传
Using an allele-specific amplification (ASA) -based genotyping method, 38 families of 9 families with CYP2D6-deficient alleles were genotyped and compared with right The comparison of the phenotypic typing of probe with probenecid showed that the results of the two methods were consistent, and the CYP2D6-deficient allele was autosomal recessive