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目的了解血红素铁对缺铁性贫血的影响。方法将符合贫血诊断的女性108人随机分为血红素铁组和对照组,并分别给予血红素铁和安慰剂,连续服用45 d,服用开始前和服用结束时对受试者进行膳食营养调查、体格检查和血液生化指标的检测并进行统计学分析。结果血红素铁组血红蛋白的含量由试验前的(106.43±10.48)g/L上升到(117.34±10.25)g/L,平均升高了10.91 g/L(服用前后配对t检验,P<0.05,服用后与对照组t检验,P<0.05);红细胞游离原卟啉的含量由(942.15±96.34)μg/L下降为(820.53±109.95)μg/L(服用前后配对t检验,P<0.05,服用后与对照组t检验,P<0.05);试验组血清铁蛋白的含量由试验前的(25.19±6.71)ng/ml上升到(25.40±6.69)ng/ml,(服用前后配对t检验,P>0.05)。结论血红素铁对缺铁性贫血具有一定的改善作用。并对受试者健康无不良影响。
Objective To understand the effect of heme iron on iron deficiency anemia. Methods A total of 108 women who were diagnosed as anemia were randomly divided into heme iron group and control group. Heme iron and placebo were given separately for 45 days. Before meals and at the end of taking food, , Physical examination and blood biochemical detection and statistical analysis. Results The hemoglobin content in heme group increased from (106.43 ± 10.48) g / L to (117.34 ± 10.25) g / L before the test, with an average increase of 10.91 g / L (paired t test before and after administration, P < (P <0.05, P <0.05). The content of erythrocyte free protoporphyrin decreased from (942.15 ± 96.34) μg / L to (820.53 ± 109.95) μg / L before and after taking the t- (P <0.05). The level of serum ferritin in the test group increased from (25.19 ± 6.71) ng / ml to (25.40 ± 6.69) ng / ml before the test (Paired t-test before and after taking the test, P> 0.05). Conclusion Heme iron has some effect on iron deficiency anemia. And no adverse effects on the health of the subjects.