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目的观察复方阿嗪米特联合胆宁片治疗胆源性消化不良的临床效果。方法 139例胆源性消化不良的患者随机分为治疗组(71例)和对照组(68例),治疗组给予复方阿嗪米特联合胆宁片治疗,对照组仅给予胆宁片治疗。分别于治疗1、2、4周末记录临床症状观察结果 ,对比两组的疗效及不良反应。结果治疗组症状明显改善,在1、2、4周时总有效率分别达40.8%、88.7%、100.0%,均明显高于对照组(19.1%、45.6%、51.5%),两组疗效比较差异有统计学意义(P<0.05)。两组不良反应及停药后复发率比较差异无统计学意义(P>0.05)。结论复方阿嗪米特联合胆宁片治疗胆源性消化不良疗效好,起效快,安全性好。
Objective To observe the clinical efficacy of compound azinamid combined with Danning tablet in the treatment of gallstone dyspepsia. Methods A total of 139 cases of gallstone dyspepsia were randomly divided into treatment group (n = 71) and control group (n = 68). Patients in the treatment group received combination of azintomide and Danning tablets, while those in the control group were given only Danning tablets. The results of clinical symptoms were recorded at the end of treatment 1, 2 and 4 respectively, and the curative effects and adverse reactions of the two groups were compared. Results The symptoms in the treatment group were significantly improved. The total effective rates were 40.8%, 88.7% and 100.0% at 1, 2, and 4 weeks respectively, which were significantly higher than those in the control group (19.1%, 45.6%, 51.5%). The difference was statistically significant (P <0.05). The two groups of adverse reactions and the recurrence rate after stopping the difference was not statistically significant (P> 0.05). Conclusion Compound azinamid combined with Danning tablet treatment of gallbladder dyspepsia effect, fast onset, good safety.