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随着女性生育年龄的推迟,年龄相关的不孕症明显增加。如何改善卵巢低反应妇女的卵巢储备功能,提高对卵巢刺激的反应性,逐渐成为研究的热点。近年来,越来越多的生殖医学中心开始使用脱氢表雄酮(DHEA)对卵巢储备功能低下的患者进行治疗。研究表明使用DHEA后可增加获卵数,改善胚胎质量,提高妊娠率,减少流产率。尽管DHEA副作用小,但是由于其有效性还缺乏足够的循证医学证据的支持,因此目前还不能被推荐在临床上广泛使用。
With the postponement of the female reproductive age, age-related infertility increased significantly. How to improve ovarian low response women’s ovarian reserve function, improve the response to ovarian stimulation, has gradually become a research hot spot. In recent years, more and more reproductive medical centers have begun to use DHEA to treat patients with poor ovarian reserve. Studies have shown that the use of DHEA can increase the number of oocytes, improve embryo quality, improve pregnancy rates and reduce abortion rates. Despite its small side effects, DHEA is not currently recommended for widespread clinical use because of its lack of adequate evidence-based medical evidence.